What you're saying doesn't stand to reason.
How is it a problem with PCs that this sim/FAQ recommends using global settings, which then subjects all other programs to those settings, and defeats the purpose of individual settings per program?
How is it a problem with PCs that this sim/FAQ recommends settings that are contradicted by every other available reference? I outlined above that the recommendations for both AA Gamma Correction and Triple Buffering are absolutely in conflict with other well-established, widely accepted and documented sources. How is that a problem with PCs?
Of course it stands to reason.
In the past with some drivers (NVidia) not ATI or dial cards or other... the global profile for some people never used to work. Others it did.
We don't just say these things for kicks as you seem to be implying. I'd much rather go do something else. 25 years experience of supporting software and PC hardware including 10+ on OFF/WOFF/WOTR tends to make you keep your options open to try things - seen some odd settings work for some people that shouldn't but there you go. One customer had to set cfs3.exe to WinXP for it to work, never had to do that myself. Others it doesn't work that way. Same OS, Same GPU. etc.
Every other reference that includes CFS3? The FAQ is from 10+ years of experience, many hundreds of support emails.
Items in there, are because some people benefited from those settings. If you find it doesn't work for you, or you disagree with it then don't use it.