@Fullofit - this is not ME fault. What ME displays (and what you show us) is WOFF generated route/flightplan without any ME modification. Without ME you would just never notice this.
Yes, it sometimes happens, however, this is question for Devs.
Triple-J, that doesn't make sense. If I fly this exact mission without ME, all flights will reach the target (or at least will attempt it) so WOFF can't be blamed. It's only if I apply ME settings when this occurs as ME doesn't have that target waypoint. I obviously know nothing about this technical stuff, but it looks like ME drops the target waypoint (or doesn't receive it from WOFF) for the escorted flights during CAS missions. I know it sounds far fetched, especially that everything else works flawlessly in ME.