Not with MMJoy2 and Win10 ...Erichos has suggested using Firmware 2016-08-18_Upd. rather than the new 2016-11-01 version though, due to the odd bug in MMjoy2 like it not reporting Axes in the "Used" Box like I have.
it is here : 2016-8-18 FIRMWARE Just make sure that the Firmware location is correct on the Firmware Tab before hitting the Arduino Reset button.