Star Citizen, Elite:Dangerous I don't know.
"Kosmosimov" xwing is not my "beach".


Other "Flight Game" that support more than 32 buttons is IL-2 Battle of Stalingrad.

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But as this game have only "toggle" options (press a key to turn something ON, press the same key to turn OFF) - "to be accessible for new players" - so SVMapper/Hidmacros can be useful for example use ON/OFF latch switch (SPST) to turn OF and OFF cockpits lights... etc.
Because SVMapper/Hidmacros can send keys commands on PRESS and in RELEASE of this switch.

If don't use SVMapper or similar will be limited to use DPST switch and wire both poles on same button, or optocoupler ic/relays circuits.