The Wii Remote connects to PC via bluetooth. But the Nunchuck is an accessory that connects to the Wii Remote and communicates with it using I2C.
couple places make a breakout board for the connector but the Nunchuck sells for like $10 so getting one to cut the cord open is no big thing either. It's only 4 wired to deal with anyway; Voltage, Ground, SCL, and SDA.
I think it would make a nice supplemental thruster control for Elite: Dangerous for landing or whatever, or a dedicated map control. I'm pretty sure I can use an old arduino pro mini or an ATtiny chip if I can get it to talk SPI to MMjoy and I2C to nunchuck at same time.
