Oh yea.
The enterprising two-seater crew was not adverse to a little one on one with a enemy two-seater, or balloon for that matter, if the situation was good.
At least for the crazy RFC boys. I have read several accounts.
Have read about a couple of French hard-chargers in the 3 place Caudron that they treated like a "gun ship."
And I am sure the Germans played that game too if the situation was right.