here is my best try with resmone.exe result
image mode
I see only CPU overload here...
... click on "CPU" tab (second from left), then organize the "Processes" window by "Average CPU" (larger numbers at the top).
Do some screenshot while you experience the slowdown.
Also there are some peaks on the Hard disk, so click on "Disk" tab, then on the "Disk Activity" window and arrange it by "Total (B/sec)".
(higher on the top)
Do some screenshot while you see those peaks happening.