Yes, set number of devices to 2 or more. Now you'll see you have 2 more cd-rom devices listed.
It doesnt matter if you install the game via one of the fake drives with a disc-image or not. LB2 can see the cd/image in any real or fake cd-drive.
When you start the game just make sure both images are mounted in two separate fake cd-drives. That way you'll never be asked to change discs mid-game. Also, LB2 doesnt have any copy-protection so no need for the original discs anymore when you mount images in daemon.