Mary Jame Watson was the redhead (who he eventually married) but there was also Gwen Stacy. While Watson is probably the most well known I would say that Gwen Stacy probably had the largest impact on spiderman and the comic as a whole.
There was also Felicia Hardy, actually In canon Peter Parker never went to school with Mary Jane Watson, he did not met her until later, and she was not his first and only love. The First series has taken a lot out of canon, though I quite liked it. This new rebot seem to go away from cannon too, but I'm excited to see what comes of it.
P.S. Also hated the "bio" web thing.