Do not clean your registry. It's a waste of time and if you do, we will be seeing you here soon asking how to fix it. The cleaners are useless and just give you the feeling you are doing something useful when in actuality you are just scrambling something that can really get very screwed up making your system unbootable.
The cleaners are very good at hosing a perfectly good system though. If you must, go in and manually remove the offending registry entry. If you must ask how, it's better to leave it alone.
At the least, make a good system image before you clean the registry.
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MSI P55-GD65 with i5-750 @ 4.0Ghz vcore 1.370
Xigmatek Balder HS/2 120mm fans, Antec EW PSU EA750 750W
GSKILL Ripjaws 2x4Gb DDR3 1333
One 2Tb Seagate LP, two 1.5Tb LP Seagates
Gigabyte GTX 460 1Gb OC to within an inch of it's life
Lite-On 24X DVD burner, LG 12X Blu-Ray burner
COOLER MASTER Storm Scout
Win 7 Pro 64
Lots of fans spinning with little LED lights blinking
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