OC the RAM will pay dividends you will never see. Fastest way I know to bring about instability and BSOD though. Better to OC that CPU and keep the RAM at stock speeds. Most mobos will run the RAM timings at spec anyway. The thing about OC is that your memory is tied to the CPU so there are memory dividers that change the relationship of the memory speed to the CPU speed so when the CPU is running faster, the memory does not, keeping the memory in spec. Some memory will OC quite a bit, but most wont OC a bit and is just not worth the effort IMHO. Beside the fact that to OC memory in a meaningful way will require more voltage and memory can go up in a puff of smoke with too much voltage since it is not protected like most CPUs are from over-voltage.
That CPU will max out around 4.3Ghz in my experience. That will require voltage in the range of 1.48 to 1.55 which is more than Intel recommends. Keep it at or below 1.45 and that should be the maximum voltage you want and you should get close to or right at 4Ghz. People that run a i5 750 at 4.5Ghz with a high vcore will reduce the life of the CPU to roughly 2 or 2.5 years, but don't care since they will upgrade to something else as it will be obsolete before it goes poof. To run at 4.5Ghz would require 1.8 or more vcore which can burn mobo contact pins too, so the risk of not only smoking the CPU but the mobo too is great if you are not conservative. Another side effect of super high suicide run OC is when the thing crashes or BSOD, it's much worse than a normal crash and can corrupt the OS totally making it un-bootable.
That CPU likes odd multipliers too. 20 is the stock multiplier and some boards can go above that to 21. If yours will, that's good. Mine won't, at least with any stability. So I run mine at 19. Or you can just leave it at 20 and set the CPU speed to 200. 20 times 200 is 4.0Ghz.
The easiest OC will be to leave the vcore at auto and set the multiplier to 20 and the speed at 185 which will get you 3.7Ghz. Most of the the 750 will do that with no additional voltage and run like that from now on.
Problems occur with OC like mine where the vcore for the CPU is raised to reach a higher OC. Higher voltage will reach higher OC, but can massively increase heat. Like I can set my vcore to 1.6 and run my CPU at 4.3Ghz. So a lot more voltage for very little increase in CPU cycles. I have a direct contact heatsink with a push-pull fan set up, two 120mm that run wide open all the time.
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MSI P55-GD65 with i5-750 @ 4.0Ghz vcore 1.370
Xigmatek Balder HS/2 120mm fans, Antec EW PSU EA750 750W
GSKILL Ripjaws 2x4Gb DDR3 1333
One 2Tb Seagate LP, two 1.5Tb LP Seagates
Gigabyte GTX 460 1Gb OC to within an inch of it's life
Lite-On 24X DVD burner, LG 12X Blu-Ray burner
COOLER MASTER Storm Scout
Win 7 Pro 64
Lots of fans spinning with little LED lights blinking
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