650W is all AMD requires for 2x HD5870 CrossFire. Probably, that's enough for 2x GTX460. Hopefully, the Nvidia site should give the power requirement -- as should the "instructions" that came with the GPU.
The best PSUs are "single rail". Some power supplies are "multi-rail". The power is split among multiple 12V rails (almost like separate PSUs in one box adding up to 750 -- but much less individually). In some cases, too many items plugged into the same rail over stresses that rail. Just a thought. Something to check, if one thinks one has a problem.
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