I've punted. Got a full tower last new build. I like the space -- in particular for the graphics cards.
Under the desk, it really takes up no "useful" extra space. And, the extra height puts the buttons (on top front) and DVD drive in a more reachable place.
On sale, the price was under $100 -- better than most of the "popular" mid towers.
For me, works out great in every way. Guess it depends on one's situation.
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ATI HD4870 512MB, ATI650 HD Tuner, Phenom II 940 @3.35GHz, 4x2GB OCZ PC8500, ASUS M3A78-T, WDigital + 4x Seagate 7200.xx = 3TB+, Plextor DVD, PCP&C S75CF 750W, Enermax Full-Twr, 2xSony CRT (24" 16:10 + 21" 4:3), 5.1 Spkr, AT ATH-AD700 Phones, Cougar+FSSB, Saitek X52 Pro, Windows 7 HP 64b, Windows 7 RC 64b, Vista HP 64b