I would suggest you disconnect the other drives.
That's what I did, no problems.
Also, it's good to know that the "Upgrade" disks are actually full installs that can be applied to a naked HD

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I have gaming PCs that run everything from MS-DOS 6.22 to Windows 7 64-bit
Win7 Home Prem 64
i5-750
MSI P55-GD80
XFX Radeon HD 6950 2 Gig
8 Gigs Corsair DDR3 1600
2 x 1 TB WD Black SATA II HD
Plextor 24x DVD-RW
ViewSonic VA2702w 1920x1080
Antec Gamer case and 650w PS
Warthog 1663 w/ CH Pro Pedals
TIR4 w/ Clip
Logitech G110 KB