I dont think Eugene (with the greatest of respect) has the whole story there. Folk have got M1TP2 workin using a glide wrapper.
NickMow, I hope you have the answer. But first, what card and driver are you using? That works? The Glide wrapper route is a given, except that M1TP2 will crash after every mission unlike in D3D mode. But neither Glide nor D3D have been reported to work on new Nvidia drivers. If you have been able, that would be great. I've tried every adjustment on Nvidia control panel and wrapper settings. Same result as Recluse reports, every time. Lots of posts on various threads and forums wrestling with this, to no avail.
A number of us still run MTP2 on machines using ATI cards, or older Nvidia (Glide and D3D modes). But not using 1XX.XX Century series Nvidia drivers.